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A type of
drug used to treat the memory loss of Alzheimer's patients appears
to also have a modest beneficial impact on behavior and the ability
to perform everyday chores, according to researchers reporting
in the Journal of the American Medical Association.
While the
drugs called cholinesterase inhibitors provide only a modest boost
in memory for most patients, the added benefits found by the researchers
-- which could delay the need for admission to a nursing home
-- might lead to more widespread use.
The researchers
analyzed the results of 29 trials in which patients with mild
to moderate probable Alzheimer's Disease were treated for at least
1 month with a cholinesterase inhibitor. Sixteen trials included
neuropsychiatric and 18 included functional measures.
The researchers
found that patients taking the drugs did better over time on tests
that assess behavioral problems as well as the ability to perform
routine tasks.
" These
results indicate that cholinesterase inhibitors have a modest
beneficial impact on neuropsychiatric and functional outcomes
for patients with Alzheimer's Disease," the researchers concluded.
"Future research should focus on how such improvements translate
into long-term outcomes such as patient quality of life, institutionalization,
and caregiver burden."
Other
sources: Journal of the American Medical Association
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