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An international
consortium of scientists report mapping another chromosome, this
one chromosome 14 -- which is linked to a range of disorders including
early-onset Alzheimer's that can strike people in their 30s.
French scientist
Roland Heilig, part of the international consortium that did the
research, said chromosome 14 had been mapped to the "gold
standard." In the past three years, chromosomes 22, 21, and
20 have also been decoded to "gold standard" level,
with no gaps left in the genetic sequence.
Chromosome
14 comprises 87,410,661 base pairs, which are the "rungs"
that make up about 1,050 genes and gene fragments, according to
the research published in the science journal Nature.
Diseases
that can be potentially caused by genes in chromosome 14 include
early onset Alzheimer's, a severe form of Usher syndrome, which
can affect hearing and vision, and the deadly Niemann-Pick disease.
Around 200,000
Americans have early onset Alzheimer's disease, accounting for
five percent of the four million American's with Alzheimer's.
"The
identification of disease genes will help us find out how diseases
develop at a molecular level," Heilig said.
Other
sources: Nature
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