An iron deficiency may contribute to the death of brain cells found in Alzheimer's disease, according to researchers at the Children's Hospital Oakland Research Institute in California.

A reduction in the production of heme, a form of iron found in cells that promotes normal cell function, caused damage to brain cells in laboratory animals that is similar to that seen in the process of Alzheimer's disease.

Common causes of heme deficiency include aging, deficiency of iron and vitamin B6, and exposure to toxic metals such as aluminum. Iron and B6 deficiencies are especially important because they are widespread, but they are also preventable with supplementation, the researchers reported in the Proceedings of the National Academy of Sciences.

Researchers conclude that heme deficiency may be an important and preventable component of the Alzheimer's disease process.

Other sources: Proceedings of the National Academy of Sciences