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Sweden researchers report that have found that nicotine appears
to effectively reduce the accumulation of amyloid beta peptide
in the brain, suggesting that nicotine treatment may be a novel
protective therapy in Alzheimer's disease.
Researchers
at the Karolinska Institute, which conducted the study on transgenic
mice, said it observed a highly significant 80 percent plaque
reduction in the brains of mice treated with nicotine compared
to those treated with sugar water.
"Inhibition
of beta amyloid accumulation may be essential for effective therapy
in Alzheimer's disease," said Dr. David Summers, Chairman
and CEO of the biotechnology company Endovasc Ltd..
"We think
the same mechanism of action ameliorates Alzheimer's that works
on other diseases treated by Angiogenix," Summers said.
Endovasc holds worldwide rights to Angiogenix.
Other
Sources: Endovasc
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