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The first human trial of ZT-1, a highly potent acetylcholinesterase
inhibitor, has shown promise for the treatment of Alzheimer's
disease, according to H3 Pharma, the drug's manufacturer.
Ten patients
over the age of 65 received the drug in a specialized clinic in
the Netherlands with "excellent tolerability results."
The drug is
derived from Huperzine A, a highly selective acetylcholinesterase
inhibitor which has enhanced the memory in the elderly and Alzheimer's
patients.
A second phase
I trial is planned to demonstrate the drug's effectiveness in
treating the disease.
Other
Sources: H3 Pharma
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