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Memory Pharmaceuticals
Corp., a drug development company in the field of learning and
memory disorders, announced it has licensed from Bayer AG the
rights to develop and market MEM 1003, a new drug candidate for
the treatment of dementia including Alzheimer's disease.
The drug belongs
to the class of neuronal calcium channel modulators that are geared
toward regulating elevated intracellular calcium levels found
in various neurological disorders including Alzheimer's disease.
"Bayer's
new-generation neuronal calcium channel modulator has shown great
potential for the treatment of dementia," said Tony Scullion,
CEO of Memory Pharmaceuticals.
"We are pleased
that Memory Pharmaceuticals will develop MEM 1003 for this important
indication with major unmet needs," said Dr. David Ebsworth, General
Manager of Bayer AG's Pharmaceuticals Business Group.
Calcium is
linked to neuronal signaling pathways involved in learning and
memory, a process called long term potentiation. Certain calcium
levels are needed for proper functioning but elevated calcium
levels can be harmful, leading to cell death.
The action
of this new-generation calcium channel modulator is to regulate
elevated intracellular calcium levels back to normal physiological
levels to restore proper functioning and to protect neurons from
the calcium overload seen in Alzheimer's disease.
Other
sources: Memory Pharmaceuticals Corp.
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